On rural Edisto (pronounced ed-is-toh) Island, find magnificent stands of age-old oaks festooned with Spanish-moss borders, quiet streams, and side roads; wild turkeys may still be spotted on open grasslands and amid palmetto palms. Twisting tidal creeks, populated with egrets and herons, wind around golden marsh grass. A big day on the island may include shelling and shark-tooth hunting.

The small "downtown" beachfront is a mix of public beach-access spots, restaurants, and old, shabby-chic beach homes that are a far cry from the palatial villas rented out on other area islands. The outlying Edisto Beach State Park is a pristine wilderness and camper's delight. There are a number of privately owned rental accommodations—condos, villas, and homes—and Wyndham Ocean Ridge Resort offers time-share units that can be rented when available. None are on the beach, however.